Pharmacy Research Group
Priority PhD Projects
Diabetes Research Group
| Project Title | Supervisors | Contact |
|---|
Uncovering the role of non-classical islet peptides in the function of the pancreatic islets and regulation of beta cell function. |
Prof Peter Flatt, Prof NH McClenaghan |
Therapeutic utility of novel stable forms of the naturally-occurring gut peptide xenin and their potential to restore the biological action of GIP in type 2 diabetes. |
Dr Nigel Irwin, Dr Victor Gault |
Pharmacy Research Group
| Project Title | Supervisors | Contact |
|---|
Synthesis, Evaluation and Optimisation of a Novel drug Delivery System. |
Dr Bridgeen McCaughan, Prof John Callan |
Creating a structural diversity library of DNA Quadruplexes that inhibit cancer cell growth. |
Dr Mateus Webba da Silva, Prof John Callan |
An investigation of the potential biocidal activity of microbial biosurfactants against bacteria important in oral and personal hygiene. |
Prof Ibrahim Banat, Dr S McClean, Advisor: Prof R Marchant |
NICHE (Northern Ireland Centre for Food and Health) Research Group
| Project Title | Supervisors | Contact |
|---|
Vitamin B12 requirements through the lifecycle. |
Prof Helene McNulty, Dr Leane Hoey, Dr Catherine Hughes, Advisor: Prof Mary Ward |
h.mcnulty@ulster.ac.uk l.hoey@ulster.ac.uk c.hughes@ulster.ac.uk mw.ward@ulster.ac.uk |
New approaches to investigate novel gene nutrient interactions in hypertension. |
Dr Mary Ward, Prof Helene McNulty, Dr Catherine Hughes, Advisor: Prof JJ Strain |
mw.ward@uslter.ac.uk h.mcnulty@ulster.ac.uk c.hughes@ulster.ac.uk |
Understanding the relationship between psychological wellbeing and food choice. |
Dr Barbara Stewart-Knox, Dr Maresa Duffy, Dr Tracy McCrorie |
b.knox@ulster.ac.uk m.duffy2@ulster.ac.uk t.mccrorie@ulster.ac.uk bp.bunting@ulster.ac.uk |
Vitamin D and athletes. |
Dr Pamela Magee, Dr Emeir McSorley |
An investigation of the relationship between exposure to inorganic and organic mercury and disease activity in systematic lupus erythematosus? |
Dr Emeir McSorley, Prof Sean Strain, Dr Philip Allsop, Dr Pamela Magee |
Control of biofilm production in pathogenic Pseudomonas aeruginosa strains. |
Prof J Dooley, Prof I Banat, Advisor: Prof R Marchant |
The role of Nrf-2 in the anti-gentoxic effects of berry metabolites. |
Dr Chris Gill, Dr Nigel Ternan, Prof Geoff McMullan |
Transcriptional Control and Epigenetics Research Group
| Project Title | Supervisors | Contact |
|---|
Cross Talk between the Vitamin D and NF-kB Signalling Pathways Link Drug Metabolism and Inflammation. |
Dr Paul Thompson, Dr Jenny Worthington, Dr Declan McKenna |
p.thompson@ulster.ac.uk j.worthington@ulster.ac.uk dj.mckenna@ulster.ac.uk |
Investigating the mechanisms behind human imprinting disorders using model systems. |
Dr Colum Walsh, Dr Declan McKenna |
Pre-clinical evaluation of Oct-1002 to control prostate cancer malignant progression. |
Dr Jenny Worthington, Dr Paul Thompson |
Vision Science
| Project Title | Supervisors | Contact |
|---|
Development of personalised gene-silencing treatment for keratin disorders. |
Prof Tara Moore, Prof Irwin McLean (Recognised), Prof Johnny Moore (Recognised), Dr Sarah Atkinson |
Beta-amyloid accumulation and cataracts in the Down Syndrome eye. |
Dr Julie-Anne Little, Dr Kathryn Saunders, Advisor: Patrick Richardson |
The NICER study: effects of environment and diet on refractive outcome. |
Dr Kathryn J Saunders, Dr Kirsty Pourshahidi, Dr Lisa O’Donoghue, Advisor: Prof Sean Strain |
Molecular Medicine
| Project Title | Supervisors | Contact |
|---|
Towards individualizing chemotherapy combination treatments in myeloma. |
Prof Tony Bjourson, Prof Denis Alexander |
Sophorolipid-mediated inhibition of tumour growth. |
Dr Christopher Mitchell, Prof Ibrahim Banat, Advisor: Prof Roger Marchant |
The role of glycosylated acute phase response proteins on SIGLEC1 regulation of circulating macrophages in Rheumatoid Arthritus. |
Dr David Gibson, Prof Tony Bjourson |
Investigations of the neuroprotective effects of novel Oxyntomodulin analogues in animal models of Alzheimer and Parkinson’s disease. |
Prof C Holscher, Dr VA Gault |
Other PhD Projects
Project List
| Project Title | Supervisors | Contact |
|---|
Sonosensitiser loaded microbubbles as targeting drug conjugates in the treatment of cancer. |
Prof J Callan, Prof AP McHale, Dr B McCaughan |
Transfer of antibiotic resistances between human pathogenic bacteria in natural biofilms. |
Prof J Dooley, Dr PJ Naughton |
Evaluation of novel glucagon-oxyntomodulin-incretin hybrid peptide for diabetes and obesity therapy. |
Dr Victor Gault, Prof Peter Flatt |
Development of an educational resource to assist the dietary compliance of older adults (>65 years) with type 2 diabetes. |
Dr Alyson Hill, Dr Mary Mccann, Advisor: Prof B Livingstone |
Uncovering the mechanism of action and enhancing the beneficial effects of prolonged cholecystokinin receptor signalling in obesity. |
Dr Nigel Irwin, Prof Peter Flatt |
Assessing the potential of novel dual agonist peptide analogues for diabetes therapy. |
Prof Finbarr O’Harte, Prof Peter Flatt |
Physiological and biochemical characterisation of C.difficile mutants. |
Dr N Ternan, Prof G McMullan, Dr Chris Gill |
Ng.ternan@ulster.ac.uk c.gill@ulster.ac.uk g.mcmullan@ulster.ac.uk |
Isolation and characterization of phytochemicals with insulin-releasing or glucose lowering effects for the treatment of type-2 diabetes. |
Dr Yasser Abdel-Wahab, Prof Peter Flatt |
The effect of soy isoflavones on cognitive function and menopausal symptoms in early postmenopausal women. |
Dr Pamela Magee, Prof Jacqueline McCormack, Dr Liz Simpson |
Design and development of particulate carrier systems for delivery and targeting of biotherapeutics. |
Prof Paul McCarron, Dr Ahmed Faheem |
MRes Projects
NICHE (Northern Ireland Centre for Food and Health)
| Project Title | Supervisors | Contact |
|---|
Assessing the potential link between metformin usage and vitamin B12 depletion in Type 2 diabetic subjects. |
Prof Helene McNulty, Prof Finbarr O’Harte |
Development of molecular methods to study the eukaryotic gut microflora of healthy individuals. |
Dr Colm Lowery, Prof James Dooley |
The role of lactobacilli in reducing the infectious disease capacity of antibiotic resistant salmonella. |
Dr Patrick Naughton, Dr Violetta Naughton, Prof James Dooley |
Multiplex detection of Clostridium difficile using luminescent nanoparticles targeted to pathogen biomarkers. |
Dr Nigel Ternan, Prof John Callan |

