Vascular Biology Research Group
Priority Projects
Diabetes Research Group
| Project Title | Supervisors | Contact |
|---|
Exploration of key signalling pathways and molecules underlying improved hippocampal function with mono and dual therapeutics in obesity-diabetes |
Dr Victor Gault Prof Peter Flatt |
Pharmacy Research Group
| Project Title | Supervisors | Contact |
|---|
Novel non-invasive detection methods for the determination of blood electrolyte concentrations. |
Dr John Callan Dr B Callan Prof Paul McCarron |
NICHE (Northern Ireland Centre for Food and Health) Research Group
| Project Title | Supervisors | Contact |
|---|
Obesity as a determinant of inflammation and glucose metabolism |
Dr Tracy McCrorie Dr Emeir McSorley Prof Barbara Livingstone |
Can all queries regarding this project be directed to Dr Tracy McCrorie t.mccrorie@ulster.ac.uk |
Vitamin D and muscle function |
Dr Kirsty Pourshahidi Prof Sean Strain |
Can all queries regarding this project be directed to |
New approaches to investigate novel gene nutrient interactions in hypertension |
Dr Mary Ward Prof Helene McNulty |
Neurobiology Research Group
| Project Title | Supervisors | Contact |
|---|
Cell signalling pathways activated by novel incretin analogues in cultured neurons |
Dr Christian Holscher Dr V Gault |
Transcriptional Control and Epigenetics Research Group
| Project Title | Supervisors | Contact |
|---|
MicroRNA involvement in prostate cancer progression |
Dr Declan McKenna Dr Colum Walsh |
G-wires for use in biomedical nanodevices |
Dr Mateus Webba da Silva Dr John Callan Dr Bridgeen Callan |
Vascular Biology Research Group
| Project Title | Supervisors | Contact |
|---|
Vascular based therapies in a mouse model of Alzheimer’s disease |
Dr Christopher Mitchell Dr Christian Holscher |
Vision Science
| Project Title | Supervisors | Contact |
|---|
Development of personalised gene silencing treatment for keratin disorders |
Dr Tara Moore Prof Irwin McLean (Recognised) Prof Johnny Moore (Recognised) Dr Sarah Atkinson |
Other Projects
Diabetes Research Group
| Project Title | Supervisors | Contact |
|---|
Isolation and characterisation of naturally occurring bioactive compounds with insulin-releasing or glucose-lowering properties for the treatment of diabetes |
Dr Yasser Abdel-Wahab Prof Peter Flatt |
Effects and therapeutic potential of gut hormones for bone disorders |
Dr Nigel Irwin Prof Peter Flatt |
Role of novel G protein-coupled receptors in islet function and type 2 diabetes |
Dr Aine McKillop Prof Peter Flatt |
Mechanistic studies to assess the benefits of combination therapies using peptide based interventions combined with the insulin sensitizing drug metformin in animal models of diabetes. |
Prof Finbarr O’Harte Prof Neville McClenaghan |
Infection and Immunity Research Group
| Project Title | Supervisors | Contact |
|---|
Small RNAs: the role of riboswitches in modulation of gene expression in Clostridium difficile |
Dr N Ternan Prof G McMullan |
Pharmacy Research Group
| Project Title | Supervisors | Contact |
|---|
Sonosensitiser loaded microbubbles as targeting drug conjugates in the treatment of cancer. |
Dr John Callan Prof AP McHale Dr Bridgeen Callan |
Biodegradable nanoparticles as a potential delivery system for anti-metastatic Ran-GTPase peptide |
Dr Ahmed Faheem Prof P McCarron Dr Mohamed-El-Tanani (QUB) |
Ultrasound for targeted gene therapy |
Prof AP McHale Dr John Callan Dr N Nomikou |
Microbial Biotechnology Research Group
| Project Title | Supervisors | Contact |
|---|
Factors influencing horizontal gene transfer (HGT) of antibiotic resistance gene determinants between commensal organisms and pathogens recovered from the lungs of Cystic Fibrosis patients. |
Prof James Dooley Dr Patrick Naughton Prof John Moore |
Influence of diet on the function of the human gut microbiome. |
Prof Geoff McMullan Dr Chris Gill Dr Nigel Ternan |
The role of lactobacilli in reducing the infectious disease capacity of antibiotic resistant salmonella in the mammalian gut. |
Dr Patrick Naughton Prof James Dooley Dr Violetta Naughton |
Nanomedicine Research Group
| Project Title | Supervisors | Contact |
|---|
Computational modelling of decationation-dependent checkpoints |
Prof Werner Dubitzky Prof Stephen Downes |
NICHE (Northern Ireland Centre for Food and Health) Research Group
| Project Title | Supervisors | Contact |
|---|
Pre-loads in weight management: is there a role for milk? |
Dr Alison Gallagher Dr Maeve Kerr Prof Rob Welch (Advisor) |
The impact of walking on weight-management of overweight/obese adolescents and young adults. |
Dr Alison Gallagher Prof Marie Murphy |
Evaluating the contribution of antioxidant rich dietary fibre on colonic microbiota and health |
Dr Chris Gill Dr Kieran Tuohy (IASMA) Dr G McMullan |
The anti-metastatic properties of olive oil phenolics in vivo |
Dr Chris Gill Dr J Worthington Prof G McMullan |
Factors associated with weaning practices of overweight and obese pregnant women |
Dr Alyson Hill Prof Marlene Sinclair |
Transcriptional Control and Epigenetics Research Group
| Project Title | Supervisors | Contact |
|---|
Environmental epigenomics in stem cells |
Dr Diane Lees-Murdock Dr Colum Walsh |
Novel chemoprotective roles for vitamin D in prostate cancer |
Dr Paul Thompson Dr Jenny Worthington Dr Stephen McClean |
Stem cell growth and reprogramming in health and disease: the role of DNA methylation. |
Dr Colum Walsh Dr Diane Lees-Murdock |
Vascular Biology Research Group
| Project Title | Supervisors | Contact |
|---|
Quantitative bioassays to assess the activity of a selected biosurfactants (rhamnolipids and or sophorolipids) for treatment of full thickness skin wounds. |
Dr Christopher Mitchell Prof Ibrahim Banat Prof Roger Marchant |
Vascular based therapies in a mouse model of Alzheimer’s disease |
Dr Christopher Mitchell Dr Christian Holscher |
MRes Projects
Transcriptional Control & Epigenetics Research Group
| Project Title | Supervisors | Contact |
|---|
SUMOylation of Vitamin D Receptor; a molecular basis for the anti-aging effects of vitamin D? |
Dr Paul Thompson Dr Declan McKenna |
Stem cell reprogramming in health and disease: the role of DNA methylation. |
Dr Colum Walsh Dr Diane Lees-Murdock |
Diabetes Research Group
| Project Title | Supervisors | Contact |
|---|
The establishment and characterization of a specific immunoassay for glucagon in biological samples. |
Prof Finbarr O’Harte Dr Aine McKillop |
Infection and Immunity Research Group
| Project Title | Supervisors | Contact |
|---|
Validation of small RNAs in Clostridium difficile strain 630 and a DnaK disruption mutant |
Dr N Ternan Prof G McMullan |
Infection and Immunity Research Group / Pharmacy
| Project Title | Supervisors | Contact |
|---|
Multiplex detection of Clostridium difficile using luminescent Quantum dots |
Dr J Callan Dr N Ternan |


